A dual role for the transcription factor Sp8 in postnatal neurogenesis
نویسندگان
چکیده
منابع مشابه
Role of C/EBPβ Transcription Factor in Adult Hippocampal Neurogenesis
BACKGROUND The dentate gyrus of the hippocampus is one of the regions in which neurogenesis takes place in the adult brain. We have previously demonstrated that CCAAT/enhancer binding protein β (C/EBPβ) is expressed in the granular layer of the dentate gyrus of the adult mouse hippocampus. Taking into account the important role of C/EBPβ in the consolidation of long term memory, the fact that n...
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15 صفحه اولThe Production of Somatostatin Interneurons in the Olfactory Bulb Is Regulated by the Transcription Factor Sp8
Somatostatin (Som), one of the most concentrated neuropeptides in the brain, is highly expressed in the olfactory bulb (OB). However, the temporal profile by which OB somatostatin-expressing (Som+) interneurons are produced and the molecular mechanisms controlling this profile are totally unknown. In the present study, we found that all the Som+ interneurons in the mouse external plexiform laye...
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ژورنال
عنوان ژورنال: Scientific Reports
سال: 2018
ISSN: 2045-2322
DOI: 10.1038/s41598-018-32134-6